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SUGIMURA GROUP
iCeMS
Kyoto University

How do cells push and pull each other to trigger precise deformations of a tissue when shaping the body? The answer to this central question is essential for understanding the development of animal forms.

By combining mechanical and genetic perturbations along with live imaging and Bayesian force-inference, we are addressing physical principles underlying regulation of epithelial morphogenesis.

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Force inference

Hexagonal cell packing

Cell competition

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