Works

Cell competition

Live imaging of cell competition in Drosophila epithelial tissue



世界で初めて組織内細胞競合をライブで捉えた.神戸大医学部(当時)井垣研との共同研究.
Collaboration with Tatsushi Igaki lab.
NHK I shoot the movie at RIKEN BSI, not RIKEN CDB.


Mechanics of apical extrusion of transformed MDCK cells

ガン細胞排除の力学.北海道大学藤田研、大阪大学石井研との共同研究.
Collaboration with Yasu Fujita lab and Masaru Ishii lab.


References

  • Shizue Ohsawa, Kaoru Sugimura, Kyoko Takino, Tian Xu, Atsushi Miyawaki, and Tatsushi Igaki.
    Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila.
    Developmental Cell 20: 315-328 (2011) [PubMed] [The featured article of the issue]

  • Shizue Ohsawa, Kaoru Sugimura, Kyoko Takino, and Tatsushi Igaki.
    Imaging cell competition in Drosophila imaginal discs.
    Methods in Enzymology 506: 407-413 (2012) [PubMed]

  • Mihoko Kajita, Kaoru Sugimura, Atsuko Ohoka, Jemima Burden, Hitomi Suganuma, Masaya Ikegawa, Takashi Shimada, Tetsuya Kitamura, Masanobu Shindoh, Susumu Ishikawa, Sayaka Yamamoto, Sayaka Saitoh, Yuta Yako, Ryosuke Takahashi, Takaharu Okajima, Junichi Kikuta, Yumiko Maijima, Masaru Ishii, Masazumi Tada, and Yasuyuki Fujita.
    Filamin acts as a key regulator in epithelial defence against transformed cells.
    Nature Communications 5: 4428 (2014) [PubMed]